The game's biggest roadblock is still its perceived lack of quality software, or lack of software altogether. The system launched with little of interest, despite having a seemingly impressive list of titles in development. Looking back on the list that was released at E3 2010, a list that many in the games press put a lot of stock in, I've broken down the games and where they are now in terms of a North American release.
Games in red text are either cancelled or have not been revealed yet. Those in blue have been released in North America. The rest in black are either scheduled for release at some point or are still hopeful for the US.
Nintendo 3DS Upcoming Games List - E3 2010
DJ Hero 3D - Series ended
Cubic ninja - Released in June
Shin Megami Tensei - No DetailsShin Megami Tensei: Persona - No DetailsShin Megami Tensei: Devil Survivor Overclocked - Released in August, it was an upgraded version of the original DS game.
Resident Evil Revelations - Coming in February 2012
Super Street Fighter IV 3D Edition - Launch title
EA FIFA Soccer - ReleasedMadden NFL - Launch title, out of football season and not updated for 2012The Sims 3 - Launch title, Pets version coming soon
Asphalt DS - Launch title
Music Game - Missing in action
Bomberman franchise - Quietly vanishedDeca Sports Extreme - Released in SeptemberKororinpa franchise - Quietly vanished
Baseball franchise - Missing in actionContra franchise - Missing in actionFrogger franchise - Frogger 3D released in SeptemberMetal Gear Solid Snake Eater 3D - Delayed until 2012
Pro Evolution Soccer - Launch Title
Professor Layton and the Mask of Miracle - Out in Japan, no NA details recently
BloodRayne: The Shroud - Missing in actionA Boy and His Blob - Not happeningFace Racers: Photo Finish - Coming in November
Lion's Pride: Adventures on the Serengeti - Missing in actionMartha Stewart - Missing in actionWonderWorld Amusement Park - Missing in action
Harvest Moon 3D - The 3DS port of the DS Tale of Two Towns is due out this month, a new Harvest Moon (Harvest Moon: The Land of Origin) was just announced for Japan in 2012
Dragon Ball franchise - Missing in actionGundam franchise - Nothing for North America, though Japan got one.Pac-Man & Galaga Dimensions - Released in JulyRidge Racer 3D - Launch titleSuper Robot franchise - Missing in action
Animal Crossing - Still planned for 2012
Kid Icarus: Uprising - Still planned for 2012
Mario Kart 7 - Coming in Nov
nintendogs + cats - Launch titlePaper Mario - Still planned for 2012
PilotWings Resort - Launch titleStar Fox 64 3D - Released in SeptemberSteel Diver - Launch title
Crash-City GP/Crash City Mayhem - Missing in actionVS-robo/Medabot 3DS - Coming to Japan in 2012
Sonic - Sonic Generations is coming later this year or early next
Super Monkey Ball - Launch title
Chocobo Racing - Screens shown in Japanese
Dragon Quest - New Dragon Quest Heroes and Dragon Quest Monsters games are coming to Japan
Final Fantasy - Theatrhythm: Final Fantasy as well as a spiritual sequel to Final Fantasy: The 4 Heroes of Light known as Bravely Default: Flying Fairy are on their way to Japan.
Kingdom Hearts - Kingdom Hearts 3D: Dream Drop Distance is coming in 2012, confirmed for North America, but few details given
Carnival Games - Missing in action
Dead or Alive: Dimensions - Released in MayDynasty Warriors - Missing in actionNinja Gaiden - Missing in actionSamurai Warriors: Chronicles - Launch title
Lovely Lisa 3D - Missing in actionNaruto Shippūden 3D: The New Era - Released in Europe and Japan only
de Blob 2 - Missing in actionKung Fu Panda 2 - Missing in actionMarvel Super Hero Squad: The Infinity Gauntlet - Scheduled for October
The Penguins of Madagascar - Missing in actionPuss N Boots - Scheduled for November
Saints Row: Drive-By - Quietly cancelled
Assassin's Creed: Lost Legacy - CancelledCombat of Giants: Dinosaurs 3D - Launch titleDriver: Renegade - Released in AugustTom Clancy's Ghost Recon: Shadow Wars - Launch titleTom Clancy's Splinter Cell Chaos Theory - Released in April
Batman - Missing in actionLEGO - There have been a few LEGO titles
Needless to say with a good chunk of the games on this list either have been canned or are lacking any information at all, so it is important never to put too much stock in what might be coming for a system. Best to wait and see what is actually coming. This isn't to say that all the games in red are never coming out, but it's best not to hold your breath for all of them.
The other issue is that a lot of those that have been released or are still coming aren't quite what was expected. Shin Megami Tensei: Devil Survivor was listed, but the sequel is actually coming to the DS while the 3DS only got a redo of the first title. Also when most people read Final Fantasy on the list, they expected more than a rhythm game. Not that either of those titles are lacking in quality, but with the way many gamers are, expectations are usually not kept in check.
Keep this in mind for future system releases; if you don't see specifics, don't put too much stock in words alone. Lists are meaningless without something to back it up, so hold your money back until you see something that you're sure you want. I'm happy with my 3DS, but had I gone into my purchase based on the unspoken promise that list made, I would be a much unhappier 3DS owner.